Testing for Tuberculosis: Skin Test (2024)

TB skin test

The TB skin test is also known as the tuberculin skin test. If you receive a TB skin test, you will have two visits with your health care provider.

First visit

During the first visit, a health care provider uses a small needle to put some testing material under the skin on the lower part of your inner arm. The testing fluid is called tuberculin.

Second visit

After two or three days, you must return to the clinic to have the skin test read. A trained health care provider will measure the size of the bump or reaction. A positive or negative test result depends on the size of the bump or reaction.

If you cannot return after two or three days to have the test read, you will need to have a skin test again.

Who can get a TB skin test

Most people can get a TB skin test. This includes:

  • Infants,
    • Children,
      • Pregnant people,
        • People with HIV infection, and
          • People who had a negative TB skin test or an undocumented TB skin test.

            You should not get a TB skin test if you have had a severe reaction, such as a severe allergic reaction, in the past. Talk to your health care provider about the TB blood test.

            If you received the TB vaccine

            Tell your health care provider if you received aTB vaccine‎

            If you have ever received a vaccine for TB, your health care provider should recommend the TB blood test. Unlike the TB skin test, TB blood tests are not affected by the TB vaccine (BCG vaccine).

            Bacille Calmette-Guérin (BCG) is a vaccine for TB disease. The vaccine is not generally used in the United States. It is given to infants and small children in countries where TB is common. It protects children from getting severe forms of active TB disease, such as TB meningitis.

            Tell your health care provider if you have received the TB vaccine, especially if you are getting tested for TB infection because it can cause a false positive TB skin test reaction. TB blood tests are the preferred tests for people who have received the BCG TB vaccine.

            How to get tested

            You can get tested for TB at the health department or at your health care provider's office. Your health care provider will choose the TB test that is best for you. Public and private health care plans may cover TB testing costs.

            Finding a test location‎

            Contact your state or local TB program about getting tested for TB.

            TB Programs

            Two-step TB skin test

            Your health care provider may perform a two-step TB skin test if you are going to be screened for TB periodically (for example, if you are a health care worker).

            Some people with inactive TB, also called latent TB infection, have a negative reaction to the TB skin test when tested years after being infected. However, if they are tested again within a year of the first test, they may have a positive reaction. The first TB skin test can "trigger the memory" of the immune system, boosting its ability to react to the second TB skin test.

            It may appear that these people were infected between the first and second tests. However, the second positive test reaction is actually a boosted reaction due to TB infection that occurred a long time ago.

            The two-step TB skin test can lower the chance that a boosted reaction from an old TB infection will be misinterpreted as a recent infection. If the reaction to the first-step TB skin test is classified as negative, a second-step TB skin test is given one to three weeks after the first test is read.

            Understanding TB skin test results

            Positive TB skin test

            A positive skin test result for TB infection means you have TB germs in your body.

            Keep a record of your positive test result‎

            Once you have a positive TB blood test or TB skin test result, you may still have a positive test result on future TB tests. This includes even after you finish taking all of your TB medicine for inactive TB or active TB disease.

            Ask your health care provider for a written record of your positive TB skin test result. This will be helpful if you are asked to have another TB test in the future.

            Negative TB skin test

            A negative skin test result for TB infection means inactive TB or active TB disease is unlikely, but your health care provider may do more tests, especially if:

            • You have symptoms of active TB disease, like
              • Coughing,
                • Chest pain,
                  • Fever,
                    • Weight loss, or tiredness.
                    • You have HIV.
                      • You were recently exposed to TB germs.

                        After you get your results

                        If you have a positive TB skin test result, you have TB germs in your body. Your health care provider will do other tests to determine if you have inactive TB or active TB disease. These tests may include a chest x-ray, and a test of the sputum (phlegm) you cough up.

                        Your health care provider will discuss your diagnosis with you and recommend treatment.

                        Keep Reading:Diagnosing Tuberculosis

                        Resources

                        What You Need to Know About the TB Skin Test Fact Sheet

                        Learn what to expect when getting a TB skin test.

                        What You Need to Know About Tuberculosis Fact Sheet

                        Use this fact sheet to learn basic information about tuberculosis (TB).

                        Questions and Answers About Tuberculosis Booklet

                        Questions and Answers About TB has information on inactive TB and TB disease.

                        Testing for Tuberculosis: Skin Test (2024)

                        FAQs

                        How to read TB skin test results? ›

                        If you have an Mtb infection, the skin around the injection site should start to swell and harden within 48 to 72 hours . This bump, or induration, may also change color. But the induration's size, not the color, will determine your results. An induration of less than 5 millimeters (mm) is a negative result.

                        What is a normal response to a TB skin test? ›

                        Normal Results

                        A negative reaction usually means you have never been infected with the bacteria that cause TB. With a negative reaction, the skin where you received the PPD test is not swollen, or the swelling is very small.

                        How do you know if you failed a TB skin test? ›

                        Your health care provider MUST check your arm 2 or 3 days after the TB skin test, even if your arm looks OK to you. If you have a reaction to the test, it will look like a raised bump. Your health care provider will measure the size of the reaction. If there is a bump, it will go away in a few weeks.

                        What does skin look like if TB test is positive? ›

                        Results. Redness alone at the skin test site usually means you haven't been infected with TB bacteria. A firm red bump may mean you have been infected with TB bacteria at some time. The size of the firm bump (not the red area) is measured 2 to 3 days after the test to find out the result.

                        Is skin test accurate for TB? ›

                        A TB skin test detects if a patient has ever been infected with TB but does not determine if a patient currently has TB infection or TB disease. Further testing is required to confirm or rule-out a diagnosis of TB disease.

                        What happens if I accidentally scratch my TB test? ›

                        After the test, you should avoid using bandages, putting on lotion, or scratching the test area because it may affect the results.

                        How big is a positive TB skin test? ›

                        The area where the skin test was given will be examined for a reaction. The nurse will measure this reaction; the TB skin test is positive if the reaction is 10mm or larger. In certain situations, we use 5mm as a positive test. Your health care practitioner will explain your result.

                        Does TB skin test need to be read? ›

                        A tuberculin skin test may be applied on the same day as routine immunizations. The skin test will need to be read 48-72 hours later.

                        Is it normal to have no reaction to TB skin test? ›

                        If there is no reaction after 2-3 days, you most probably have not been exposed to the TB germ. If there is a reaction, some redness and a small bump will appear on the arm. A measurement of 10 millimetres or more is "positive", and means you may have the TB germ in your body.

                        How to read tuberculosis blood test results? ›

                        Negative results suggest that there is not TB infection. In patients with high suspicion of exposure, a negative test should be repeated. A positive test indicates infection with Mycobacterium tuberculosis. Among individuals without tuberculosis infection, a positive test may be due to exposure to M.

                        What if my TB test is red but no bump? ›

                        It does not mean you have an active TB infection. The test may be seen as positive if the skin where you were injected is hard, raised, red, and swollen. But redness alone is not considered a positive test result. In many cases, a healthy immune system will surround the TB bacteria soon after you are infected.

                        Can I read my own TB skin test? ›

                        The tuberculin skin test must be given and read by a professional who has been trained to do this, and has been informed of the most recent guidelines in tuberculosis control. Never allow anyone other than a nurse or physician to read a tuberculin skin test.

                        How long does it take to get results of a TB skin test? ›

                        Results will not be available on the same day you have the test. You must return to the healthcare provider 48-72 hours after the test is administered to have the results read and receive the required form.

                        How to interpret TB skin test? ›

                        Fifteen mm or more is positive in

                        Persons with no known risk factors for TB. Reactions larger than 15 mm are unlikely to be due to previous BCG vaccination or exposure to environmental mycobacteria.

                        Can you have a positive TB skin test and not have TB? ›

                        Some persons may react to the TST even though they are not infected with M. tuberculosis. The causes of these false-positive reactions may include, but are not limited to, the following: Previous TB vaccination with the bacille Calmette-Guérin (BCG) vaccine.

                        Does a positive TB skin test itch? ›

                        Side effects are uncommon from the Mantoux skin test. However, a person who has been exposed to TB germs may occasionally have a sizable reaction, which may cause some mild itching, swelling or irritation. These kinds of reactions should disappear in one to two weeks.

                        What not to do before a TB test? ›

                        You don't any special preparations for TB skin test or a TB blood test.

                        What can mess up a TB skin test? ›

                        Factors that can affect the results of a TB skin test include:
                        • having recent contact with another person with TB.
                        • working at a medical facility, such as a hospital, care center, or medical lab.
                        • having TB in the past.
                        • receiving an organ transplant.
                        • taking immunosuppressant drugs.
                        • being HIV positive.
                        Jun 3, 2017

                        What does a failed TB skin test look like? ›

                        Your health care provider MUST check your arm 2 or 3 days after the TB skin test, even if your arm looks OK to you. If you have a reaction to the test, it will look like a raised bump. Your health care provider will measure the size of the reaction. If there is a bump, it will go away in a few weeks.

                        How big is a negative TB skin test? ›

                        A measurement of 0 mm or a measurement below the defined cut point for each category is considered negative.

                        Can a TB skin test be injected wrong? ›

                        However, the following factors may cause a false-negative result or diminished ability to respond to tuberculin. Error in TST administration (subcutaneous injection, insufficient dose) or interpretation of reaction.

                        Why do TB tests hurt so much? ›

                        There is a very slight risk of having a severe reaction to the tuberculin skin test, especially if you've had tuberculosis (TB). An allergic reaction can cause a lot of swelling and pain at the site. You may have a sore. You cannot get a TB infection from the tuberculin skin test.

                        Can I shower after a TB skin test? ›

                        A: You can take showers and baths as you normally do. Q: What do I do if my arm itches or blisters? A: Put an ice cube in a washcloth and place it on your arm. DO NOT SCRATCH!

                        How do you read a TB skin test code? ›

                        Namely, that if a patient presents for interpretation of the results of a PPD (purified protein derivative of tuberculin) test, it is appropriate to report CPT code 99211. CPT code 86580 is reported for the Mantoux test using the intradermal administration of purified protein derivative (PPD).

                        What is the normal range for TB test results? ›

                        The reference range of the induration is 0-15 millimetres at an increment of 5 mm, 10 mm and 15 mm. An induration size of more than 15 mm is considered positive in a normal patient.

                        What is a positive induration for TB skin test? ›

                        An induration of 5 or more millimeters is considered positive in: People with HIV. Recent contacts of people with infectious TB disease. People with chest x-ray findings suggestive of previous TB disease.

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