RESORCINOL
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Chemical Component Summary | |
|---|---|
| Name | RESORCINOL |
| Synonyms | 1,3-BENZENEDIOL; 1,3-DIHYDROXYBENZENE |
| Identifiers | benzene-1,3-diol |
| Formula | C6 H6 O2 |
| Molecular Weight | 110.111 |
| Type | NON-POLYMER |
| Isomeric SMILES | c1cc(cc(c1)O)O |
| InChI | InChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H |
| InChIKey | GHMLBKRAJCXXBS-UHFFFAOYSA-N |
Chemical Details | |
|---|---|
| Formal Charge | 0 |
| Atom Count | 14 |
| Chiral Atom Count | 0 |
| Bond Count | 14 |
| Aromatic Bond Count | 6 |
Drug Info: DrugBank
| DrugBank ID | DB11085 |
|---|---|
| Name | Resorcinol |
| Groups | approved |
| Description | Resorcinol is a 1,3-isomer (or meta-isomer) of benzenediol with the formula C6H4(OH)2. It is used as an antiseptic and disinfectant in topical pharmaceutical products in the treatment of skin disorders and infections such as acne, seborrheic dermatitis, eczema, psoriasis, corns, calluses, and warts. It exerts a keratolytic activity. Resorcinol works by helping to remove hard, scaly, or roughened skin. Although it is primarily indicated for use as a topical application, resorcinol also possesses a well-documented anti-thyroidal activity that is generally not relied upon for any kind of formal therapeutic indication. |
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| Brand Names |
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| Indication | Contemporary therapeutic uses for resorcinol primarily revolve around the use of the phenol derivative as an active ingredient in topical antiseptics [L2745, L2744, L40069, F61] or as topical antibacterial skin treatment products for conditions like acne, seborrheic dermatitis, eczema, and others [L2746, L2745, L2744, L40069, F61]. |
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| ATC-Code |
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| CAS number | 108-46-3 |
Drug Targets
| Name | Target Sequence | Pharmacological Action | Actions |
|---|---|---|---|
| Thyroid peroxidase | MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLV... | unknown |
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, JewisonT, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
Related Resource References
| Resource Name | Reference |
|---|---|
| PubChem | 5054 |
| ChEMBL | CHEMBL24147 |
| ChEBI | CHEBI:27810 |
| CCDC/CSD | GAJROB, HOLKAW, IGIZEG01, KAJFEJ, IGIZAC, ACOYOG01, EDAZOB, EDAYIU, ABEKUN03, ABEKUN02, ABELAU06, ABEKUN04, HOPKED, IGIZEG, ABEKUN01, DUVHAE01, ACOYOG, DEGQUE, ABELAU03, ABELAU02, ABELAU01, EJIXUQ, DOGCIO, ABELAU04, EBIMIM, ABELAU05, BODSAO, KIHZAD, ANUNED, GAVBAI, KEXHUR, FOSFOK, AXEZIM, ABEKUN, KEXJIH, ABELAU, DUVHAE, JORBEA, COZZUN, ABELIC, ASORIL, ITUJOX, AXOGIE, GIHBUW, CEKBOJ, BULLAX, KIJLAS, IMIWAF, IYAZEQ |
